Umunsi mpuzamahanga wa Arthritis ni umunsi wo kumenyekanisha ubuzima ku isi wateguwe buri mwaka ku ya 12 Ukwakira hagamijwe gukangurira abantu kwirinda indwara ya rubagimpande na musculoskeletal, ingaruka zayo ku buzima bw’umuntu no kwigisha abantu ibimenyetso & ingamba zo gukumira no kuyobora indwara yo kwisuzumisha hakiri kare kugira ngo bahangane n’izindi ngaruka zose. .
Akamaro k'umunsi mpuzamahanga wa rubagimpande (WAD)
Indwara ya Arthritis ni indwara ifata ingingo, ifata ingingo zifatanije ingingo zifatanije, hamwe nizindi ngingo zihuza, bigatera ububabare hamwe no gukomera.Ubwoko burenga 100 bwa rubagimpande burahari, ariko cyane cyane ni osteoarthritis na rubagimpande ya rubagimpande.Bitewe no kutamenya no gushyigikirwa, arthrite nubuzima bwayo bifitanye isano nubumuga bwisi yose kwisi.Nta buryo bwihariye bwo kuvura indwara ya rubagimpande, uburyo bwo kuvura buratandukanye bitewe n'ubwoko, bityo rero ni ngombwa kumva ibimenyetso & ibimenyetso hanyuma ukabona kwisuzumisha hakiri kare kugirango ubone ubuvuzi bukwiye.
Uburyo bukunze kugaragara bwa rubagimpande
Ubwoko bukunze kugaragara harimo osteoarthritis (OA), rubagimpande ya rubagimpande (RA), arthrite ya psoriatic (PsA), fibromyalgia na gout.Indwara ya rubagimpande n'indwara zifitanye isano nazo zirashobora gutera ububabare, guhindura ubuzima muburyo butandukanye.
Indwara ya rubagimpande (RA) ni imwe mu ndwara zikunze kwibasira ingingo, zikunze kugaragara ku bagore bageze mu za bukuru.Ahanini igaragara nka karande, ihuza, polyarthrite itera imbere.Usibye kugira ingaruka ku ngingo, hari byinshi bigaragara bidasanzwe, nk'uruhu, amaso, umutima, ibihaha, sisitemu y'amaraso, n'ibindi.
Indwara ya RA ni 0.5-1%, hamwe n’umugore ku kigereranyo cya 3: 1.Irikubye inshuro 4 kugeza kuri 5 kubagore bari munsi yimyaka 50, ariko nyuma yimyaka 60 igipimo kiba hafi 2 kugeza 1.Abantu barwaye rubagimpande ya rubagimpande akenshi bafite urwego rwo hejuru rwa C-reaction proteine (CRP), ibyo bikaba bishobora kwerekana ko umubiri uhari.Ibindi bipimo bisanzwe byamaraso bireba ibintu bya rubagimpande (RF) na antibodiyite anti-cyclic citrullinated peptide (anti-CCP).
RA(Indwara ya rubagimpande)
Indwara ya rubagimpande ni indwara idakira ishobora kwanduza ingingo zawe gusa.Mu bantu bamwe, indwara irashobora kwangiza sisitemu zitandukanye z'umubiri, zirimo uruhu, amaso, ibihaha, umutima n'amaraso.
Indwara ya autoimmune, rubagimpande ya rubagimpande ibaho mugihe sisitemu yumubiri wawe yibeshye yibice byumubiri wawe.
Bitandukanye no kwangirika kwangirika kwa osteoarthritis, rubagimpande ya rubagimpande igira ingaruka kumurongo wurugingo rwawe, bigatera kubyimba kubabaza amaherezo bishobora kuviramo isuri kumagufa no guhindagurika.
Anti-CCP Irwanya Cyclic Citrullinated Peptide Antibody
Antibody anti-cyclic citrullinated peptide (Anti-CCP): Ni agace ka polypeptide ya proteine cyclic polyguanidine kandi ahanini ni antibody yo mu bwoko bwa IgG.Antibodiyite anti-cyclic citrullinated peptide zihita zisohoka na lymphocytes B z'abarwayi barwaye rubagimpande ya rubagimpande (RA), mugihe lymphocytes B y'abarwayi bafite izindi ndwara hamwe nabantu basanzwe ntibahita basohora antibodiyite anti-cyclic citrullinated peptide.Kubwibyo, ifite ibyiyumvo byinshi kandi byihariye kuri rubagimpande ya rubagimpande, kandi ni ikimenyetso cyihariye cyo gusuzuma hakiri kare indwara ya rubagimpande.
Anti-CCP (Anti-cyclic citrullinated peptide) ni ubwoko bwa autoantibody: antibody ikora irwanya antibodi zisanzwe z'umubiri wawe.Anti-CCP ikunze gukorwa mugihe ufite rubagimpande ya rubagimpande.Izi autoantibodies zitangira kwibasira no gutera ubundi tissue nzima.
Ibipimo byo kwisuzumisha hakiri kare ya rubagimpande ya rubagimpande: antibodiyide anti-cyclic citrullinated antibodies igaragara mbere yimyaka 1-10 mbere yuko ivuriro ryerekana indwara ya rubagimpande ya rubagimpande, ibereye kwisuzumisha kumubiri kubantu bafite ubuzima bwiza no gusuzuma hakiri kare amatsinda afite ibyago byinshi.Kugeza ubu,abantu bemeza ko ubukangurambaga bwa antibodiyide anti-cyclic citrullinated peptide yo gusuzuma indwara ya rubagimpande ya rheumatoide ari 50% kugeza kuri 78%, umwihariko ni 96%, kandi igipimo cyiza cy’abarwayi bo hambere gishobora kugera kuri 80%.
AehealthAnti-CCP Pumusaruro
Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Ikizamini cyihuse cyerekana uburyo bwa Immunofluorescence Assay.
Kurwanya umurongo wa anti-CCP ni 10 ～ 500 U / mL;ihuriro rifitanye isano hagati yubushakashatsi hamwe nubunini bwapimwe bushobora kugera kuri 0,990.Ikoreshwa hamwe na Aehealth Lamuno X isesengura immunofluorescence kugirango iherekeze gusuzuma hakiri kare gusuzuma no kuvura abarwayi ba rubagimpande.
Antibodiyite zirwanya CCP zifitanye isano nibikorwa bya RA.
Antibodiyite zirwanya CCP zihanura ibyangiritse RA.
Igihe cyo kohereza: Ukwakira-12-2022